Steve Morison sent League One Millwall into the last 16 of the FA Cup as his 85th-minute volley knocked out Premier League Watford.
Championship side Fulham thrashed Hull City at Craven Cottage to progress to the FA Cup fifth round.
Sutton United pulled off one of the biggest shocks of this season’s FA Cup with a fourth-round win over Leeds, a team 83 league places above them.
Wigan must have wondered if they could continue the theme of Shocking Sunday but is was not to be.
Bastian Schweinsteiger marked his first Manchester United start for a year with a goal and an assist in a convincing 4-0 FA Cup win over Wigan.